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Updated: May 6, 2026

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在肝细胞中开发CYP诱导试验的考虑:来自多实验室研究的见解

Hiroko Toyoda1, Ayaka Nozue2, Yuki Nishida3

  • 1Institute of Life and Environmental Sciences, University of Tsukuba, Tsukuba 305-8572, Japan; Human Emulation System, Central Research Center, Stem Cell Evaluation Technology Research Association (SCETRA), Tsukuba, Japan.

European journal of cell biology
|June 18, 2025
PubMed
概括

使用原始人肝细胞 (PHH) 的细胞染色体P450 (CYP) 诱导研究的变化是由于种植密度和治疗时间不一致而发生的. 优化标准操作程序 (SOP) 对于提高CYP诱导试验的可重复性至关重要.

关键词:
分析方法 分析方法诱导 CYP 的诱导.多个实验室的研究.主要的人类肝细胞.标准操作程序 标准操作程序

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