相关实验视频

Updated: Jul 24, 2026

Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion

Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion

Published on: February 17, 2013

同时的MRI和激光多普勒流量计:评估神经密集护理中的大脑宏观和微循环

Sofie Tapper¹, Stina Mauritzon¹, Marcelo P Martins²

¹Department of Biomedical Engineering, Linköping University, Linköping, Sweden.

NeuroImage. Clinical

|June 18, 2025

概括

这项研究表明,使用MRI和激光多普勒流量计同时监测神经重症监护室 (NICU) 患者的大脑血流 (CBF) 的可行性. 这种新的方法提供了对大脑循环的纵向洞察,有助于预防二次大脑损伤.

科学领域:

神经科学是一个神经科学.
医疗成像医学成像
密集护理医学密集护理医学

背景情况:

脑血流 (CBF) 监测对神经重症监护室 (NICU) 患有下关节出血 (SAH) 的患者至关重要,以预防二次脑损伤.
目前在NICU的CBF监测方法有限,需要开发先进的技术.

研究的目的:

研究同时使用磁共振成像 (MRI) 与动脉旋转标记 (ASL) 和二维流动MRI,以及基于探针的激光多普勒流量计 (LDF),用于NICU患者的CBF监测的可行性.
在临床NICU环境中评估并发MRI和LDF测量的兼容性和数据质量.

主要方法:

包括4名SAH患者,其中3人接受了用于光学探针放置的例行手术.
同时的LDF和MRI测量在几天内多次进行.
对CBF数据进行了比较,使用绝对ASL CBF图,二维流动MRI衍生的总流量和LDF输液,以及每半球ASL和动脉流量之间的区域比较.

主要成果:

12次MRI测量成功完成,其中8次包括同时进行的LDF.
同时测量是可行的,而不会损害患者的安全或数据质量,通过谨慎的程序和扫描仪的NICU位置来促进.
所有方法都证明了CBF的纵向动态变化,ASL和2D流数据显示了三名患者的密切相关性 (动态变化10%以内).

结论:

这种新的方法可以同时对人类大脑中CBF的宏观和微循环成分进行纵向估计.
这种技术有望更深入地了解NICU患者不同CBF方面的相互作用.
这种方法可能有助于预防重症神经病患者的二次脑损伤.

关键词:

2D 流动MRI 2D 流动MRI 是一个二维流动MRI.动脉旋转标签 (ASL) 是指动脉旋转的标签.大脑血液流动 (CBF)神经临界护理是指神经临界护理.有光学探头的探头.脑下关节下出血 (SAH) 是一种血管的情况.

更多相关视频

Using Laser Doppler Imaging and Monitoring to Analyze Spinal Cord Microcirculation in Rat

Using Laser Doppler Imaging and Monitoring to Analyze Spinal Cord Microcirculation in Rat

Published on: May 30, 2018

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Evaluation of Cerebral Blood Flow Autoregulation in the Rat Using Laser Doppler Flowmetry

Published on: January 19, 2020

相关概念视频

Magnetic Resonance Imaging

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

Brain Imaging

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

Imaging Studies for Cardiovascular System IV: CMRI

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...