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Updated: Sep 19, 2025

A Bioluminescent and Fluorescent Orthotopic Syngeneic Murine Model of Androgen-dependent and Castration-resistant Prostate Cancer
07:25

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在前列腺癌中,ATM和ATR抑制会增加放射敏感性和cGAS-STING激活

Nina van Campen1, Vera E Mekers1, Maaike W Looman1

  • 1Radiotherapy and OncoImmunology laboratory, department of Radiation Oncology, Radboud University Medical Center, Nijmegen, the Netherlands.

Cytokine
|June 18, 2025
PubMed
概括

抑制ATM和ATR激酶会增加前列腺癌细胞对辐射的敏感性,增强细胞死亡并激活免疫通路. 这种组合疗法在治疗转移性割抵抗性前列腺癌方面表现有前途.

关键词:
这是一个ATMATMATM.这是一个ATRATRATRATR.干扰素 干扰素 干扰素前列腺癌是什么意思 前列腺癌是什么意思辐射疗法 辐射疗法cGAS 是一个气体.

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