穿孔性胃潰瘍患者的手術死亡率和發病率預測器:一組群組研究
Negin Pouroushaninia1, Ramin Bozorgmehr2, Nazanin Alibeik3
1Student Research Committee, School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.
The Journal of surgical research
|June 18, 2025
概括
这项研究确定了穿孔性胃潰瘍 (PPU) 手术患者的死亡率和发病率的关键风险因素. 管理这些因素,如年龄和并发症,可以改善患者的治疗结果,减少PPU并发症.
科学领域:
- 手术 手术 手术 术 术
- 胃肠病学 胃肠病学
- 临界护理医学 临界护理医学
背景情况:
- 穿孔性胃潰瘍 (PPU) 是全球常見的手術緊急情況.
- 及时诊断和管理对于减少显著的发病率和死亡率至关重要.
- 这项研究调查了与PPU手术结果相关的风险因素.
研究的目的:
- 为了确定PPU手术患者的死亡率和发病率的频率.
- 确定影响术后并发症和死亡率的风险因素.
- 为预防PPU外科病例的不良结果提供见解.
主要方法:
- 一项队列研究审查了102名接受PPU手术的患者的记录 (2020年9月至2023年4月).
- 在6个月内评估了术后死亡率和发病率.
- 影响因素在并发症/无并发症和死亡/活体组之间进行了比较.
主要成果:
- 该研究包括102名患者,其中87.3%是男性,平均年龄为47.56岁.
- 手术后死亡率和发病率分别为18.6%和31.4%.
- 有关并发症的重要危险因素包括年龄>60,低白蛋白,高肌/BUN,并发症,休克,增加呼吸速率,意识下降和污染. 升高的BUN,并发症,意识下降和污染与死亡率有关.
结论:
- 临床评估和及时干预对于管理PPU手术风险至关重要.
- 解决并发症和已识别的风险因素可以减轻死亡率和发病率.
- 了解这些风险因素有助于外科医生预防PPU患者的术后并发症.
相关概念视频
Peptic Ulcer Disease V: Surgical Management and Nursing Care
421
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
Surgical Interventions for Peptic Ulcer Disease
421
Peptic Ulcer Disease I: Introduction
302
Peptic Ulcer Disease (PUD) is characterized by mucosal excavation in the esophagus, stomach, pylorus, or duodenum. It can manifest as acute or chronic based on the extent and duration of mucosal involvement.
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
An acute ulcer, marked by superficial erosion and minimal inflammation, swiftly resolves upon identifying and addressing the underlying cause. In contrast, a chronic ulcer persists, potentially eroding through the muscular wall and forming fibrous tissue.
Peptic ulcers can also be...
302
Peptic Ulcer Disease III: Clinical Manifestations and Diagnostic Studies
209
Peptic ulcer disease (PUD) presents with diverse symptoms depending on the location and severity of the ulcer. Clinical manifestations of peptic ulcer include dull pain and a burning sensation in the mid-epigastric region.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
Few clinical manifestations differentiate gastric ulcers from duodenal ulcers. Distinctions in the location, timing, and pain relief are crucial for healthcare providers in differentiating between gastric and duodenal ulcers during clinical assessments.
209
Pathophysiology of Peptic Ulcer Disease: Mucosal Defense Factors
604
Peptic ulcer disease, commonly called PUD, represents a multifaceted condition characterized by disruptions in the lining of the gastrointestinal (GI) tract. Central to the protection of the gastrointestinal lining is the mucosal-bicarbonate barrier. This physiological defense mechanism is a formidable shield against the corrosive effects of gastric acid and pepsin secretion in the stomach. Its role is pivotal in maintaining the structural integrity of the stomach's inner lining.
604
Pathophysiology of Peptic Ulcer Disease: Injurious Factors
728
Peptic ulcers are sores on the stomach's inner lining and the upper small intestine, which are the result of disruptions in the mucosal layer that houses parietal cells which produce gastric acid, and chief cells which secrete pepsinogen.
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
In the antrum region, G cells secrete the gastrin hormone that binds to gastrin-cholecystokinin-B (CCK2) receptors on parietal and enterochromaffin-like (ECL) cells in the fundic glands. Simultaneously, the vagus nerve releases acetylcholine, which binds...
728
Peptic Ulcer Disease II: Pathophysiology
893
Peptic Ulcer Disease (PUD) is characterized by the development of ulcers in the stomach or duodenal mucosa. Its pathophysiology is complex, involving a balance between damaging and protective elements.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
Damaging agents such as Helicobacter pylori, gastric acid, pepsin, and nonsteroidal anti-inflammatory drugs (NSAIDs) can weaken the mucosal defense, allowing hydrogen ions to infiltrate back and harm epithelial cells.
893


