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在非吸烟者中,二手烟暴露,孕妇怀孕期间吸烟和中风发病率之间的关联
Yi-Ping Huang1, Wei-Dong Fan2, Ying Feng3
1Jieyang People's Hospital, Jieyang, China.
概括
在非吸烟者中,暴露于二手烟 (SHS) 和孕妇怀孕期间吸烟显著增加了中风风险. 联合暴露带来了最高的风险,凸显了对烟草控制的必要性.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 心血管疾病研究研究
背景情况:
- 调查环境烟草烟雾暴露对心血管健康的影响.
- 了解怀孕期间母亲吸烟对后代的长期健康后果.
研究的目的:
- 确定二手烟 (SHS) 暴露和孕妇在怀孕期间吸烟对非吸烟者的中风风险的独立和联合影响.
- 分析与全中风,缺血性中风和出血性中风的关联.
主要方法:
- 对336,640名没有先前心血管疾病的非吸烟者进行前性队列研究.
- 评估SHS暴露 (小时/周) 和母亲吸烟史.
- 利用考克斯回归来分析在11.8年的中位数随访期间中风发病率.
主要成果:
- 暴露于SHS>4小时/周增加了中风风险 (HR 1.34).
- 母亲吸烟使得整体中风风险增加了7% (HR 1.07).
- 结合SHS暴露 (>4小时/周) 和母亲吸烟的风险最高 (HR 1.57).
结论:
- 暴露于SHS和母亲吸烟都与增加中风风险独立相关.
- 对SHS和母亲吸烟的联合暴露显著增加了中风风险.
- 调查结果强调了全面的烟草控制政策的迫切需要.
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