在神经事件边界的HPC-DMN集成影响跨边界的BOLD表示和记忆回忆
Qiuyi Liu1, Siyang Li2, Lili Sun1
1School of Life Science and Technology, HIT Faculty of Life Science and Medicine, Harbin Institute of Technology, Harbin 150001, China; Research Center for Social Computing and Interactive Robotics, Harbin Institute of Technology, Harbin 150001, China.
NeuroImage
|June 18, 2025
概括
大脑中的神经事件边界有助于我们回忆回忆. 大脑活动在这些边界的变化,特别是在海马体综合体 (HPC) 和默认模式网络 (DMN) 中,有助于记忆回忆.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 记忆研究 记忆研究
背景情况:
- 连续的经验通过事件边界被细分为离散的事件.
- 这些边界与海马综合体 (HPC) 和默认模式网络 (DMN) 内大脑活动的显著转变有关.
- HPC和DMN对于学习和记忆形成至关重要.
研究的目的:
- 调查HPC-DMN区域的神经事件边界如何促进事件回忆.
- 检查网络集成和边界对齐对内存回忆的影响.
- 了解跨界BOLD模式转移和神经事件网络形成的作用.
主要方法:
- 使用了夏洛克fMRI数据集.
- 分析了17名人类参与者的功能磁共振成像 (fMRI) 数据.
- 调查了事件边界的BOLD模式不相似性和网络属性.
主要成果:
- 较大的跨界BOLD模式不相似性在下叶 (IPL) 与成功的事件回忆相关.
- 这种效应在具有高网络集成 (参与系数) 或与前上旋 (aSTG) 或腹侧前额叶皮层 (vlPFC) 保持一致的边界处明显.
- 内皮质促进了回忆的事件链接,特别是在低参与系数的边界或与准海马体 (PHC) 的对齐处.
结论:
- 神经事件边界对于自然环境中的记忆理解和回忆至关重要.
- 在事件边界的HPC-DMN区域之间的相互作用,受网络集成和对齐的影响,支持记忆形成.
- 特定的大脑区域,如IPL,脑内皮层和它们的连接,在处理记忆回忆的事件边界方面发挥着不同的作用.
相关概念视频
01:14Role of Cerebellum and Prefrontal Cortex in Memory
606
The cerebellum, while traditionally associated with motor control, also plays a crucial role in memory, particularly in procedural memory, which involves learning motor tasks that become automatic through repetition. For example, studies have shown that when the cerebellum is damaged, individuals or animals lose the ability to learn conditioned motor responses, such as the conditioned eye-blink response in classical conditioning experiments with rabbits. This study demonstrates the...
606
01:05Cerebral Hemispheres
571
The human brain, a complex organ, is functionally divided into two cerebral hemispheres—left and right. These hemispheres are interconnected by a structure of paramount importance, the corpus callosum. This substantial bundle of neural fibers is not just a bridge between the hemispheres but a crucial element for the brain's comprehensive functioning. It enables efficient communication between the two hemispheres, allowing each side of the brain to control and receive sensory and motor...
571
01:26Higher Mental Functions of Brain: Learning and Memory
976
Memory is one of the most vital higher mental functions of the brain. Memory is closely related to learning because it enables us to retain information and experiences from our past to use them in our present life. It also helps us to remember facts, events, and skills, such as riding a bike or swimming. There are two types of memory — declarative memory, which involves memorizing facts or events, and procedural memory, which enables us to remember how to do something like writing or...
976
01:19Role of Hippocampus in Memory
567
The hippocampus, a critical brain structure, plays an essential role in memory processing, particularly in the formation and retrieval of memory. This small, seahorse-shaped region is located within the medial temporal lobe, with one hippocampus in each brain hemisphere. Experimental studies involving lesions in the hippocampi of rats have demonstrated significant impairments in tasks such as object recognition and maze navigation, indicating the hippocampus involvement in both recognition and...
567