转变农业化学品的评估:一个概念模型
Bhuller Yadvinder1, Bishop Patricia2, Cope Rhian3
1Interdisciplinary School of Health Sciences, University of Ottawa, Ottawa, ON, Canada.
Regulatory toxicology and pharmacology : RTP
|June 18, 2025
概括
监管机构现在可以将科学进步纳入农业化学品风险评估中,使用新的农业化学品评估 (TEA) 模型. 这一框架为日益增长的全球人口提高了食品安全和质量.
科学领域:
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
- 监管科学 监管科学
背景情况:
- 监管机构面临的挑战是将新的科学和技术进步纳入农业化学风险评估框架.
- 为不断增长的全球人口确保食品安全和质量,需要调整这些监管方法.
研究的目的:
- 开发一个概念模型,将科学和技术进步纳入农业化学品安全评估中.
- 引导监管机构采用农业化学品风险评估的新方法和最佳实践.
主要方法:
- 召集了一个由国际科学家组成的多方利益相关者委员会.
- 开发了转变农业化学品评估 (TEA) 概念模型.
- 纳入了一种分层的方法,具有连续的元素:暴露主导,适应性和新科学的纳入,被额外的层包围.
主要成果:
- 该TEA模型整合了十个元素,包括适合目的,全球/本地适应,激励,数据共享,透明度和信任.
- 到目前为止,这种新型模型还没有在任何监管数据包中同时实施.
- 通过指导原则和两个监管应用示例来证明模型的实用性.
结论:
- TEA概念模型提供了一个结构化的方法来转变农业化学评估.
- 它支持通过系统地纳入新科学来超越下一代风险评估.
- 该模型是加强农业化学品安全监管实践的工具.
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