多种微量营养素补充对预防怀孕期间贫血的作用:一项回顾性队列研究
Junhui Zhong1,2, Nan Li1,2, Junxi Chen1,2
1Institute of Reproductive and Child Health/National Health Commission Key Laboratory of Reproductive Health, School of Public Health, Peking University, Beijing, 100191, China.
Nutrition & metabolism
|June 18, 2025
概括
多重微量营养素 (MMN) 补充剂显著降低了怀孕晚期贫血风险. 早期和频繁摄入MMN和叶酸 (FA) 与单独FA相比,显示出更大的益处.
科学领域:
- 产科和妇科 产科和妇科
- 营养科学 营养科学
- 公共卫生 公共卫生
背景情况:
- 怀孕期间的贫血是一个重要的全球健康问题,影响着母亲和胎儿的结果.
- 微量营养素缺乏导致贫血,需要有效的补充策略.
研究的目的:
- 评估多种微量营养素 (MMN) 补充剂在降低孕妇贫血风险方面的疗效.
- 为了比较MMN补充剂与单独使用叶酸 (FA) 对贫血患病率的影响.
主要方法:
- 一个回顾性队列研究,涉及4,239名孕妇.
- 仅接受叶酸 (FA) 和FA加MMN补充剂的组之间的比较.
- 血红蛋白水平的分析和统计评估,使用奇平方测试和逻辑双项回归.
主要成果:
- 服用MMN补充剂在第二和第三季度显著降低了贫血风险 (在第三季度调整RR为0.844).
- 足够的每月摄入MMN (≥24片) 与第二和第三季度的贫血风险较低有关.
- 在第一季度,MMN的疗效是有限的.
结论:
- 补充MMN是有效的减少贫血的风险在怀孕的第二和第三个三个月.
- 早期和频繁的MMN和FA补充剂的启动提供了对贫血的更大保护.
- 有针对性的MMN补充策略对于改善孕产妇健康结果至关重要.
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