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Updated: Sep 19, 2025

Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments
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Microfluidic Co-Culture Models for Dissecting the Immune Response in in vitro Tumor Microenvironments

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解码癌症动态:通过O信息和社区检测进行干细胞标记物相互作用的超图分析

David H Margarit1,2,3, Marcela V Reale1,2,3,4, Gustavo Paccosi3,5

  • 1Universidad Nacional de General Sarmiento, Instituto de Ciencias (ICI)-, (UNGS), J. M. Gutiérrez 1150, Los Polvorines, Buenos Aires, Argentina.

Physical review. E
|June 19, 2025
PubMed
概括

这项研究使用了超图模型来绘制跨器官癌症干细胞标记物相互作用的图. 它揭示了这些标记物如何影响瘤的进展和转移,有助于多器官治疗的发展.

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相关概念视频

Cancer Stem Cells and Tumor Maintenance02:40

Cancer Stem Cells and Tumor Maintenance

Early diagnosis and treatment can often cure cancer. However, even with treatment, residual cells called cancer stem cells (CSC) might remain, often causing tumor recurrence. These cancer stem cells possess the potential for self-renewal and multi-lineage differentiation and are often responsible for the therapeutic resistance displayed in most cancers.
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Adaptive Mechanisms in Cancer Cells02:53

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Distinctive Features of Adult Stem Cells vs Cancer Stem Cells

A stem cell is an unspecialized cell that can divide without limit as needed and can, under specific conditions, differentiate into specialized cells.
Adult stem cells
Adult stem cells are tissue-specific; hence, they divide to develop the tissue from which they originate. One type of adult stem cell is the epithelial stem cell, which gives rise to the keratinocytes in the multiple layers of epithelial cells in the epidermis of the skin. Adult bone marrow has three distinct types of stem cells:...
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Cancer Survival Analysis01:21

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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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