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Updated: Sep 19, 2025

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合成的铁甲基兰衍生物的抗糖尿病潜力:来自体外研究,分子对接,ADMET,DFT计算和分子动力学模拟的见解

Yahia Bekkar1, Elhafnaoui Lanez1,2, Touhami Lanez1

  • 1Laboratory of Valorization and Technology of Sahara Resources (VTRS), Faculty of Exact Sciences, Department of Chemistry, University of El Oued, El Oued, Algeria.

Biotechnology and applied biochemistry
|June 19, 2025
PubMed
概括

三种新的铁甲基兰衍生物显示出作为糖尿病治疗的α-氨基酶抑制剂的显著潜力. 与阿卡尔相比,FMBA和FMAA在体外表现出更高的疗效和稳定性,这表明有希望的治疗应用.

关键词:
在ADMET分析中,分析了ADMET.DFT计算的计算方法模拟MDMD的模拟它具有抗糖尿病活性.铁甲基兰的衍生物铁甲基兰衍生物.分子对接的分子对接.抑制α-氨基酶的抑制.

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