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新型PI3kδ抑制剂罗吉诺西布在血液性恶性瘤中与venetoclax协同作用

Binu Kandathilparambil Sasi1, Chiara Tarantelli2, Stephen Martindale1

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School; Boston, Massachusetts.

Haematologica
|June 19, 2025
PubMed
概括

作为PI3Kδ抑制剂的罗吉诺利西布在治疗DLBCL和CLL等B细胞淋巴瘤时,与venetoclax表现出协同作用. 这种组合针对关键的亡蛋白,支持血液恶性瘤的临床发展.

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