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Updated: Sep 19, 2025

Author Spotlight: Generating Neuronal Phenotypic Profiles - A Protocol to Culture and Image Human Midbrain Dopaminergic Neurons
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一个3D模式模型用于PDAC中侵入性表型和药物敏感性的可复制性表征

Sophie C Kurzbach1,2,3, Violetta Carvajal-Heckele1,2,3, Tetsuhiko F Teshima4,5

  • 1TUM School of Natural Sciences, Department of Bioscience, Heinz Nixdorf Chair in Biophysical Engineering of Living Matter, Technical University of Munich, 85748 Garching, Germany. abausch@tum.de.

Lab on a chip
|June 19, 2025
PubMed
概括

一个新的3D模式平台标准化了胰腺癌建模. 它量化了亚型入侵和药物反应,改善了针对个性化医学的临床前研究.

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EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
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