没有异常胎儿生长的早产婴儿的芬顿第三代生长图表:系统审查和元分析
Tanis R Fenton1, Seham Elmrayed2, Belal N Alshaikh1,3
1Community Health Sciences, Alberta Children's Hospital Research Institute, O'Brien Institute of Public Health, Cumming School of Medicine, University of Calgary, Calgary, Canada.
Paediatric and perinatal epidemiology
|June 19, 2025
概括
新的芬顿生长图为早产婴儿生长评估提供了更好的标准. 这些性别特定的图表与胎儿生长估计相一致,提高了早产婴儿的准确性.
科学领域:
- 新生儿学和产周医学
- 儿科生长与发展 儿科生长与发展
- 生物统计学和流行病学
背景情况:
- 准确评估早产婴儿的生长是至关重要的,理想情况下使用胎儿生长模式.
- 由于子宫内生长限制,估计早产婴儿的健康胎儿生长存在挑战.
- 当前的增长图表可能不能充分代表该人口的健康增长轨迹.
研究的目的:
- 开发最新的,性别特定的芬顿早产期生长图表,使用没有异常胎儿生长的婴儿的数据.
- 通过与胎儿生长标准保持一致,加强对早产婴儿生长的评估.
- 评估新图表所描绘的增长速度的一致性和准确性.
主要方法:
- 对早产婴儿 (孕期≤24周出生) 基于人口的性别特异的人类测量数据进行了系统审查,没有异常的胎儿生长.
- 包括来自15个国家的7项研究的数据,代表了超过480万例出生 (174,184例早产).
- 使用元分析协调体重,长度和头部周长数据,并将妊娠年龄尺度调整为确切的周和天.
主要成果:
- 芬顿第三代早产期生长图表显示了百分位数的更好,更均的斜率.
- 体重,长度和头周长的增长速度随着月经后年龄的增加而持续下降.
- 出生体重元分析曲线与胎儿超声波估计值非常相似,表明准确度有所提高.
结论:
- 更新的芬顿早产生长图为早产婴儿提供了更准确和更一致的生长标准.
- 这些图表更好地反映胎儿生长模式,有助于评估早产婴儿的发育.
- 与胎儿超声波估计的改进对齐,提高了它们在监测早产婴儿的临床实用性.
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