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Updated: Sep 19, 2025

Anticancer Metal Complexes: Synthesis and Cytotoxicity Evaluation by the MTT Assay
11:14

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针对线粒体的复合物通过扰乱铁的平衡来发挥强大的抗癌活性

Qi-Xin Guan1,2, Long-Bo Yu1,2, Peng Wang1,2

  • 1MOE Key Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry, Sun Yat-Sen University, Guangzhou 510275, P. R. China.

ACS pharmacology & translational science
|June 19, 2025
PubMed
概括

一种新的复合物Ti-DFX-TPP有效地针对三阴性乳腺癌 (TNBC) 的铁代谢. 这种方法通过增加活性氧物种 (ROS) 来扰乱癌细胞的生长,并且对TNBC治疗有希望.

关键词:
铁的平衡是铁的平衡.线粒体功能障碍 线粒体功能障碍抑制的增殖抑制的增殖.复合物的复合物传递的变化是传递的.

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