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对于严重的角质瘤,结合交叉链接的侧膜晶体添加角质塑性术后的角质表面变化

Xi-Yu Sun¹, Di Shen¹, Hao-Xi Chen¹

¹Xi'an No.1 Hospital; Shaanxi Institute of Ophthalmology; Shaanxi Key Laboratory of Ophthalmology; Clinical Research Center for Ophthalmology Diseases of Shaanxi Province, First Affiliated Hospital of Northwestern University, Xi'an 710002, Shaanxi Province, China.

International journal of ophthalmology

|June 19, 2025

概括

通过 Femto-second 激光辅助的树叶晶状体添加角质塑造 (SLAK) 与交叉链接 (CXL) 稳定了严重的角质. 早期的术后变化,称为"伪进展",并不表明疾病的实际进展.

科学领域:

眼科医生眼科眼科
角膜外科手术角膜外科手术
生物医学工程生物医学工程

背景情况:

角膜是一种渐进的角膜脱光,导致视力受损.
雌二秒激光辅助状晶状体添加角膜整形术 (SLAK) 是治疗角质的一种手术选择.
交叉链接 (CXL) 增强角膜刚性,并且经常与角膜整形手术相结合.

研究的目的:

为了评估SLAK与CXL相结合的早期 (3个月) 角膜反应,在形患者中.
为了分析前后角膜曲率和升高后手术后的变化.
为了区分早期的术后变化和实际的角质进展.

主要方法:

对20只眼睛进行了前性观察研究,这些眼睛患有SLAK + CXL的角质.
角膜形态指数 (角质测量,高度) 用Sirius测量在基线,1个月和3个月.
分析前后角膜曲率 (Kmax,K1,K2) 和最佳适合球体 (BFS) 的高度变化.

主要成果:

前角膜曲率 (K1,K2) 在1个月后显著增加,在3个月后稳定.
后角膜曲率 (K1,K2) 在1个月后在3mm午线上显著下降.
前部BFS在1个月后显著下降,后部BFS没有变化;前部和后部升高向后移动,稳定了3个月.

结论:

近视SLAK与CXL相结合,提供了一种经济的方法来稳定严重角膜炎的角膜.
观察到早期的术后角膜变化 ("伪进展"),但并不意味着角质的进展.
结合SLAK和CXL程序在前3个月内显示出对角膜表面的稳定作用.

关键词:

添加添加添加添加交叉链接是指交叉链接.形 (keratoconus) 是一种形.一个lenticule,一个lenticule.小切口镜片提取小切口镜片提取

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