对于前100名儿科药物的无质选择
Kelly L Matson1, Clara L Forbes2, Katelyn E Burton3
1Department of Pharmacy Practice (KLM), University of Rhode Island, Kingston, RI.
概括
许多儿科药物含有质,对患有乳症的儿童构成风险. 这项研究评估了顶级儿科药物的无质状态,发现了显著的变化和不完整的制造商数据.
科学领域:
- 儿科药理学 儿科药理学
- 胃肠病学 胃肠病学
- 食品科学 食品科学 食品科学
背景情况:
- 越来越多的人被诊断为患有乳病和对质敏感,特别是在儿童中.
- 确定药物质含量的现有资源往往不完整,专注于成年人.
- 对于特定于儿科药物的精确质信息有着极大的需求.
研究的目的:
- 评估100种最常使用的儿科药物的无质状态.
- 鉴定因药物质含量而导致腹腔疾病的儿科患者的潜在风险.
- 为了突出有关儿科药物质水平的当前信息的空白.
主要方法:
- 通过使用Optum Clinformatics Data Mart数据库,确定了前100种儿科药物.
- 获得了每个已识别的药物的国家药物代码 (NDC) 和制造商信息.
- 直接联系药品制造商,询问质含量和交叉污染协议.
主要成果:
- 对689个NDC的分析显示,50.2%的儿科药物被记录为无质.
- 很大一部分药物无法确认无质状态或交叉污染 (22.6%确认无质,但交叉污染未知;25.7%无法确认无质状态).
- 只有1.5%的评估药物被证实含有质,但数据可能随着制造业的变化而演变.
结论:
- 儿科药物表现出不同的质含量,与成人配方不同.
- 显而易见的是,关于儿科药物的质含量,缺乏全面和可访问的信息.
- 为儿童药物质含量开发专门的资源对于支持患有乳症的儿童至关重要.
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