影响人类结肠微生物群的饮食模式从婴儿期到百岁的年龄:一个叙述性回顾
Vitor Geniselli da Silva1,2, Nicole Clémence Roy1,2,3, Nick William Smith1
1Riddet Institute, Massey University, Palmerston North, New Zealand.
Frontiers in nutrition
|June 19, 2025
概括
饮食模式在所有生命阶段都对肠道微生物群产生重大影响. 富含水果,蔬菜和发酵食品的特定饮食促进有益的肠道微生物和代谢物,改善健康.
科学领域:
- 微生物学 微生物学
- 营养科学 营养科学
- 胃肠病学 胃肠病学
背景情况:
- 饮食极大地影响着结肠微生物群,在人类健康和疾病中起着至关重要的作用.
- 关于饮食微生物群相互作用的现有研究主要集中在成年人身上,忽视了婴儿期和老年成人等关键生命阶段.
- 通过饮食策略调节结肠微生物群是健康和疾病预防越来越感兴趣的领域.
研究的目的:
- 审查各种饮食模式对整个人类寿命的结肠微生物群的影响,从婴儿期到百岁的年龄.
- 确定特定年龄的饮食建议,支持健康的肠道微生物群,促进整体健康.
- 突出饮食与结肠微生物群相互作用领域的知识差距和未来研究方向.
主要方法:
- 这项研究是一个叙事综述,综合了现有的关于不同生命阶段饮食微生物群相互作用的文献.
- 该评论分析了各种饮食模式,包括富含水果,蔬菜,全谷物,发酵食品,鱼类和瘦肉类的饮食模式.
- 它讨论了这些饮食模式对结肠微生物多样性,特定细菌种群和代谢产生的影响.
主要成果:
- 多样化的饮食丰富的水果,蔬菜和全谷物,补充发酵食品和适度的鱼/瘦肉摄入量,增强结肠微生物的多样性.
- 这些饮食模式促进了糖溶性细菌的丰富性,并增加了有益的微生物代谢物的产生.
- 结肠微生物群的组成和功能在不同生命阶段有很大差异,需要根据年龄特定的饮食考虑.
结论:
- 饮食干预可以有效调节结肠微生物群,促进整个生命周期的健康.
- 未来的研究应该专注于个性化的营养策略和先进的方法,如在模拟,以更深入地了解饮食-微生物群相互作用.
- 将传统研究与计算建模相结合,可以加速所有年龄组的个性化营养进步.
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