甘油三指数-葡萄糖指数和过活性膀综合征:来自NHANES 2005-2018年的证据
Baitong Chen1,2,3, Jiongming Wang1,3, Yueting Huang1,3
1The First School of Clinical Medicine, Guangdong Medical University, Zhanjiang, China.
Frontiers in endocrinology
|June 19, 2025
概括
甘油三糖 (TyG) 指数与过度活性膀 (OAB) 的更高风险有关. 这种关联在女性和年轻人中更强烈,这表明TyG是OAB的潜在查工具.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 代谢健康 代谢健康
- 流行病学 流行病学
背景情况:
- 甘油三指数 (TyG) 与膀过活 (OAB) 之间的关系需要进一步研究.
- 了解这种联系可能有助于早期发现和管理OAB.
研究的目的:
- 检查TyG指数与发展OAB的风险之间的关联.
- 探索这种关联中的剂量反应关系和子组变异.
主要方法:
- 国家健康和营养检查调查 (NHANES) 数据 (2005-2018) 的分析.
- 利用了后勤回归模型和受限立方线 (RCS) 曲线.
- 进行子组和相互作用分析以确定特定的人口特征.
主要成果:
- 总共分析了14059名参与者,其中3325人被诊断为OAB.
- TyG指数的每一个单位增加与OAB风险增加1.18倍相关.
- 较高的TyG指数四分位数显示OAB风险显著增加,通过RCS分析观察到正线性关联.
结论:
- TyG指数与OAB风险有积极的关联.
- 这种关联在60岁以下的个人和女性中更为明显.
- TyG指数可以作为早期OAB查的具有成本效益的标志物,特别是在那些有代谢异常的人中.
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