在肺移植后的静脉血栓塞栓症
Thirugnanasambandan Sunder1, Paul Ramesh Thangaraj2, Madhan Kumar Kuppusamy2
1Department of Heart Lung Transplantation and Mechanical Circulatory Support, Apollo Hospitals, Chennai 600086, Tamil Nadu, India. sunder64@gmail.com.
World journal of transplantation
|June 19, 2025
概括
静脉血栓栓塞 (VTE) 是肺移植 (LT) 后的严重风险,影响患者的康复和长期结果. 早期诊断和管理对于改善这种救命手术后的生存率至关重要.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 移植手术 移植手术
背景情况:
- 肺移植 (LT) 是对末期肺病的最终治疗方法,越来越多的患者接受该程序.
- 等待LT的患者通常会出现诸如晚年,虚弱和肺部损伤等并发症,增加静脉血栓栓塞 (VTE) 的风险.
- 在重症患者中,使用体外膜氧化 (ECMO) 作为通往LT的桥梁,进一步增加出血和血栓栓塞的风险.
研究的目的:
- 审查肺移植后的VTE的发病率,临床特征和诊断方法.
- 检查目前的治疗策略,潜在的并发症和与LT后VTE相关的患者结局.
- 突出VTE,特别是肺栓塞 (PE) 对移植功能和LT后长期存活的影响.
主要方法:
- 关于肺移植受体VTE研究的文献综述.
- 对有关VTE发生率,表现和诊断的临床数据的分析.
- 在LT的背景下,综合有关VTE治疗,并发症和结果的信息.
主要成果:
- VTE是LT后的一种已知的并发症,与增加的发病率和死亡率有关.
- 移植肺中的肺栓塞 (PE) 可以损害气体交换,使右心室紧张,并危及支气管缩的愈合.
- 静脉瘤可能会导致慢性肺异位移植功能障碍的发展,影响长期的移植存活.
结论:
- VTE对接受和从LT中康复的患者构成重大威胁.
- 及时识别和有效管理VTE对于优化肺移植接受者的结果至关重要.
- 需要进一步研究为LT人群量身定制的VTE预防和治疗策略.
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