基于CT扫描的阴暗化-发育比的应用,用于诊断儿科慢性鼻炎
Jun Zhang1, Anni Yang1, Tengyu Chen1
1Department of Otolaryngology, Head and Neck Surgery, The Fifth Affiliated Hospital of Sun Yat-Sen University, Zhuhai, Guangdong Province, People's Republic of China.
Therapeutics and clinical risk management
|June 19, 2025
概括
阴暗化-发育比 (ODR) 在CT扫描上显示了儿科慢性鼻炎的强大诊断潜力. 这种新的ODR评分在诊断幼儿时特别有效,优于传统的隆德-麦凯评分.
科学领域:
- 放射学 放射学是一门学科.
- 儿科耳鼻喉科 儿科耳鼻喉科
- 医疗成像医学成像
背景情况:
- 儿童慢性鼻炎 (CRS) 诊断仅仅使用临床症状可能具有挑战性.
- 计算机断层扫描 (CT) 扫描经常使用,但可以产生高的错误阳性率.
- 需要客观的评估工具来提高儿童的诊断准确性.
研究的目的:
- 评估儿科CRS的阴暗化-发育比 (ODR) 的诊断性能.
- 为了将ODR与儿童建立的隆德-麦凯 (LM) 评分进行比较.
- 确定ODR在不同儿科年龄组中的实用性.
主要方法:
- 对1820名0-15岁儿童的鼻腔CT扫描进行了回顾性分析.
- 计算每个患者的ODR和LM分数.
- 使用接收器操作特征曲线 (AUC) 下的面积和预测值来评估诊断准确性.
主要成果:
- 在所有年龄组的ODR和LM得分之间发现了显著的正相关性.
- 在0-15岁儿童中,ODR (AUC 0.7970) 的诊断准确度与LM (AUC 0.7719) 的诊断准确度相当.
- 在0-4岁的儿童中,ODR表现明显优越 (p < 0.001),具有高特异性 (94.2%),最佳切线为25.83.
结论:
- ODR是基于CT的有价值的工具,用于诊断儿科CRS.
- 在较小的儿童 (0-4岁) 中,ODR显示出特别强的诊断能力.
- 该ODR可能有助于提高诊断准确性和减少儿科CRS评估中的错误阳性.
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