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Updated: Sep 19, 2025

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Sexual Crosses with the Mucoromycete Phycomyces blakesleeanus
Published on: June 6, 2025
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对螺旋体诱导的细胞质不相容性产生男性依赖的耐药性
Marie Pollmann1,2,3, Ronja Reinisch2, Lea von Berg2,4
1Koret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, Hebrew University of Jerusalem, Rehovot, Israel.
Royal Society open science
|June 19, 2025
概括
细胞质不相容性 (CI) 是由细菌引起的胚胎失败. 在Lariophagus distinguendus黄蜂中,CI耐药性在一些菌株中取决于雄性,这表明细菌损失的进化驱动因素.
科学领域:
- 进化生物学是进化的生物学.
- 微生物遗传学微生物遗传学
- 昆虫与微生物的相互作用
背景情况:
- 细胞质不相容 (CI) 导致受感染的男性和未受感染的女性之间的胚胎失败.
- 非敏感宿主中CI耐药性的机制尚不清楚.
- 寄生虫黄蜂Lariophagus distinguendus携带了Spiroplasma,一种诱导CI的内生生物.
研究的目的:
- 调查L.distinguendus类的螺旋等离子体相关性.
- 确定CI发生率和宿主/性别对诱导的影响.
- 确定非敏感黄蜂菌株的耐药性机制.
主要方法:
- 螺旋菌株的多部位序列类型化 (MLST).
- 在不同宿主群和性别之间进行CI测定.
- 螺旋菌株的实验性交叉转移.
主要成果:
- 所有的L. distinguendus分类都携带相同的Spiroplasma菌株 (sDis).
- 在A类中观察到CI,但在B和C类中不存在.
- 叶片B表现出男性依赖的CI耐药性,由交叉转移实验证实.
结论:
- 一个单一的Spiroplasma感染事件可能发生在L. distinguendus类的祖先中.
- 依赖男性的耐药性是CI耐药性演变的关键因素.
- 这些发现为研究螺旋体诱导的CI机制和耐药性提供了基础.
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