肌酸补充对癌症患者身体组成的影响:系统性审查
Asier Del Arco1, Saioa Aguirre-Elordui1, Jurgi Olasagasti-Ibargoien1
1Health, Physical Activity and Sports Science Laboratory, Department of Physical Activity and Sports, University of Deusto, Bilbao, Spain.
Nutrition and cancer
|June 19, 2025
概括
肌酸补充剂 (CrS) 对癌症患者的体质成分具有有限的显著影响. 虽然它通常是安全的,但它对癌症患者的益处需要进一步的研究,特别是在不那么激烈的治疗方法下.
科学领域:
- 营养科学 营养科学
- 在瘤学瘤学.
- 运动医学 运动医学
背景情况:
- 肌酸是一种天然存在的化合物,对肌肉能量至关重要.
- 饮食和补充剂是肌酸的来源.
- 新兴研究表明,在慢性疾病中具有潜在的治疗作用.
研究的目的:
- 审查肌酸补充剂对癌症患者或癌症幸存者的身体组成的影响.
- 综合当前关于肌酸对体重,肌肉质量和脂肪质量的影响的证据.
主要方法:
- 在遵守PRISMA指南的基础上进行系统审查.
- 搜索了五个数据库,搜索到9月12日之前的相关研究.
- 分析了7篇涉及463名参与者的文章 (316名男性,147名女性;平均年龄62.95岁).
主要成果:
- 体重变化不一致:三项研究没有发现影响,两项报告增加.
- 瘦肉体质量显示在肌酸和安慰剂组增加,但没有统计学意义.
- 脂肪质量结果是可变的,包括减少,没有变化或在激素治疗期间减弱增加.
结论:
- 目前,癌症患者补充肌酸可显著改善身体成分的证据有限.
- 肌酸补充似乎对癌症患者来说是安全的.
- 潜在的益处可能在接受不那么激烈的治疗或患有非转移性疾病的患者中更为明显.
- 需要进一步的研究来确定肌酸在癌症治疗和身体组成管理中的作用.
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