风险因素和预测模型为手术前的下肢静脉血栓瘤在老年妇女经历Colpocleisis
Xiaoxiang Jiang1,2, Stefano Manodoro3,4, Chaoqin Lin5,6
1Department of Gynecology, Fujian Maternity and Child Health Hospital, 18 Dao-shan street, Gu-lou District, Fuzhou, 350000, China.
International urogynecology journal
|June 19, 2025
概括
手术前的下肢静脉血栓塞 (LEVT) 影响15.3%的老年妇女接受骨器官缩 (POP) 的结肠切除术. 一个新的预测模型有助于早期风险分层,以改善患者的治疗结果.
科学领域:
- 妇科 妇科 妇科 妇科
- 血管外科 血管外科
- 老年病的医生 老年病的医生
背景情况:
- 针对晚期骨盆器官脱落 (POP) 进行科尔科克利西斯的老年妇女面临手术前下肢静脉血栓形成 (LEVT) 的风险增加.
- 风险因素包括老年,运动能力受限和并发症.
研究的目的:
- 在这个患者群体中确定LEVT的患病率.
- 确定LEVT的独立风险因素.
- 开发和验证LEVT风险分层的预测模型.
主要方法:
- 对340名因晚期POP而接受囊治疗的老年妇女进行了回顾性研究 (2019年8月 - 2024年9月).
- 多普勒超声波用于LEVT诊断.
- 单变量和多变量逻辑回归用于风险因素识别.
- 基于nomogram的预测模型开发和验证通过五倍交叉验证.
主要成果:
- 手术前的LEVT患病率为15.3% (52/340名患者).
- 独立的危险因素包括晚年,先前的静脉血栓栓塞,恶性瘤,高胆固醇和高D-二次体水平.
- 预测模型显示出良好的区别 (AUC 0.824培训,0.806验证) 和临床效用.
结论:
- 显著的百分比的老年妇女接受了colpocleisis现有手术前的LEVT.
- 开发的预测模型为早期风险评估提供了一个实用的工具.
- 预计将改善术后管理和患者的治疗结果.
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