接受内分泌治疗的乳腺癌患者的症状负担和症状集群:一个横截面调查
Baojin Han1,2, Simeng Ren1, Jiayue Jin1,2
1Guang'anmen Hospital, China Academy of Chinese Medical Sciences, No. 5, Beixiange Street, Xicheng District, Beijing, 100053, China.
概括
乳腺癌患者在中国使用传统中医 (TCM) 经历了症状集群,困难睡眠和热发汗显著影响生活质量.
科学领域:
- 在瘤学瘤学.
- 综合医学是一个整体的医学.
- 症状科学 症状科学
背景情况:
- 在中国,许多乳腺癌患者在治疗期间使用传统中医 (TCM) 来治疗症状.
- 乳腺癌的内分泌疗法可能导致各种与治疗相关的症状,影响患者的福祉.
研究的目的:
- 在接受内分泌治疗的乳腺癌患者中识别和描述症状集群,这些患者也寻求TCM治疗.
- 研究这些症状集群对这些患者的生活质量 (QoL) 的影响.
主要方法:
- 招募了214名接受内分泌治疗和TCM的乳腺癌患者队列.
- 使用M.D.来评估症状负担. 安德森症状目录-中国传统医学 (MDASI-TCM) 和乳腺癌特定问卷.
- 患者的生活质量 (QoL) 用单项QoL尺度进行评估.
主要成果:
- 最常见的中度至重度症状包括睡眠障碍 (57%),记忆困难 (49%),出汗 (42%),疲劳 (41%) 和痛苦 (39%).
- 确定了六个不同的症状集群:痛苦-睡眠障碍,乳腺-性功能障碍,与疲劳相关的,发热-出汗,疼痛-关节硬,便秘-苦味.
- 困境睡眠障碍和热发汗集群显著与降低的QoL相关.
结论:
- 在接受内分泌治疗和在中国使用TCM的乳腺癌患者中发现了六个症状集群.
- 困境睡眠障碍和热发汗集群需要特别的临床关注,因为它们对QOL有很大的负面影响.
- 综合临床和人口因素对于这种患者群体的有效症状管理至关重要.
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