目前的进展和挑战在最小侵入性食道切除术中
Eisuke Booka1, Hiroya Takeuchi2
1Department of Surgery, Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-Ku, Hamamatsu, Shizuoka, 431-3192, Japan.
International journal of clinical oncology
|June 19, 2025
概括
最少侵入性食道切除术 (MIE) 与食道癌的开放性手术相比,显示出非劣势的生存率,肺部并发症较少. 这支持MIE作为标准治疗的采用,尽管需要对长期结果进行进一步的研究.
科学领域:
- 手术瘤学手术瘤学
- 最少侵入性的手术
- 胸部外科手术 胸部外科手术
背景情况:
- 由于内镜和胸腔镜设备的进步,极少侵入性食道切除术 (MIE) 的采用正在增加.
- 与开放性食道切除术 (OE) 相比,MIE提供了优势,包括减少血液损失和减少肺部并发症,尽管手术时间较长.
- 患者的定位 (左侧形与倾斜) 和特定的MIE技术仍然是争论的主题.
研究的目的:
- 与开放性食道切除术 (OE) 相比,评估微创食道切除术 (MIE) 的疗效和安全性.
- 评估机器人辅助和介质镜方法在食道切除术中的作用.
- 提供支持采用MIE作为标准治疗方式的证据.
主要方法:
- 综述了近期内镜和胸腔镜外科设备的进展.
- 对胸腔镜食道切除术 (TE) 患者定位策略的分析.
- 包括来自随机第三期试验 (JCOG1409) 的数据,比较TE和OE.
主要成果:
- 胸腔镜食道切除术 (TE) 在胸腔食道癌的整体存活率方面与开放式食道切除术 (OE) 不逊.
- 包括机器人和介质镜技术在内的MIE与较低的肺部并发症率有关.
- 与OE相比,MIE保持了可比的瘤结果.
结论:
- 最少侵入性食管切除术 (MIE) 是开放性食管切除术 (OE) 的可行替代方案,在减少术后呼吸道并发症方面具有证明的好处.
- 这些发现支持采用MIE作为食道癌症的标准治疗方法.
- 未来的研究应该专注于长期成果和机器人协助在MIE的最佳整合.
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