对乳腺癌治疗中新辅助化疗的研究趋势的可视化:一个文献计量分析
Tian Tian1, Chao Li1, Chao Hu1
1Department of General Surgery, Beijing Luhe Hospital, Capital Medical University, Beijing, 101149, China.
Discover oncology
|June 19, 2025
概括
本文献分析揭示了乳腺癌研究新辅助化疗 (NAC) 的关键趋势. 它确定了主要的贡献者,并突出了研究差距,特别是在三阴性乳腺癌 (TNBC) 中,敦促进行更多的合作试验.
科学领域:
- 在瘤学瘤学.
- 图书统计学 图书统计学
- 医疗信息学 医疗信息学
背景情况:
- 新辅助化疗 (NAC) 对于乳腺癌治疗至关重要,旨在在手术前减少瘤大小.
- 虽然乳腺癌的NAC研究正在增长,但缺乏全面的文献计量和临床分析.
- 本研究解决了对该领域的演变和关键贡献进行系统概述的需求.
研究的目的:
- 在乳腺癌研究中对新辅助化疗 (NAC) 进行文献分析.
- 识别有影响力的研究,作者和研究趋势.
- 为未来的研究方向提供见解,并识别知识缺口.
主要方法:
- 从1999年到2024年发表的11505篇文章的图书统计分析,来源于科学网络核心集合 (WoSCC).
- 使用VOSviewer,CiteSpace,以及用于数据分析的"bibliometrix"套件.
- 分析包括出版物数量,作者贡献,期刊影响力和关键词的同时出现.
主要成果:
- 美国在NAC乳腺癌研究中的出版物和有影响力的文章方面处于领先地位.
- 关键的研究人员包括Sibylle Loibl,Michael Untch和G. Von Minckwitz,Von Minckwitz是最常被引用的作者.
- 研究热点侧重于生存率,手术前化疗疗效和整体治疗策略,对三阴性乳腺癌 (TNBC) 的正电子发射断层扫描越来越感兴趣.
结论:
- 该研究绘制了NAC乳腺癌研究的格局,确定了关键参与者和不断发展的趋势.
- 确定的研究缺陷包括有限的国际合作和对像TNBC这样的侵略性亚型的治疗策略未经探索.
- 需要进行更多高质量的临床试验,以提高 NAC 乳腺癌的个性化治疗和反应预测.
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