微塑料环境相关度的生物积累和次慢性毒性 在Etroplus suratensis水鱼中
Bini C Das1, Vineetha V P1, Devika Pillai1
1Department of Aquatic Animal Health Management, Kerala University of Fisheries and Ocean Studies, Kochi, Kerala, India.
Ecotoxicology (London, England)
|June 19, 2025
概括
这项研究表明,聚乙烯微塑料在盐水鱼组织中生物积累,导致显著的生理和氧化应激. 这些发现凸显了微塑料污染对水生生态系统的有毒影响.
科学领域:
- 环境科学 环境科学
- 水生毒理学 水生毒理学
- 生态毒理学 生态毒理学
背景情况:
- 微塑料污染在水生态系统中普遍存在.
- 关于微塑料生物积累和对水鱼类物种的影响的研究有限.
研究的目的:
- 研究聚烯微塑料 (PS-MPs) 在幼珍珠斑 (Etroplus suratensis) 中的生物积累和毒理作用.
- 评估PS-MPs在各种鱼类组织和生理参数中的分布和影响.
主要方法:
- 青春期珍珠斑被暴露在1微米PS-MPs的不同度 (0,0.2,2,4毫克/升) 中,持续14天.
- 分析了微塑料在组织中的分布 (胃肠道,,肝脏,脏,肌肉,大脑).
- 测量了生物化学标记物 (血清葡萄糖,蛋白质,胆固醇,肝酶),抗氧化剂状态 (SOD,CAT,GPx,TAC,MDA,PC) 和基因表达 (NRF2,P53,HSP70,IGF1,CYP1A).
主要成果:
- 在所有分析的组织中检测到PS-MPs,其中肠道的度最高,大脑的度最低.
- 暴露导致血清生物化学发生变化,抗氧化能力下降,氧化应激标志物增加.
- 暴露PS-MP调节了与细胞应激反应和解毒通路相关的关键基因表达,包括NRF2,P53,IGF1和CYP1A的下调和HSP70.0的上调.
结论:
- 这项研究提供了第一个关于PS-MP在水鱼组织中的生物积累在环境相关度下的全面数据.
- PS-MPs在珍珠斑中引起显著的生理和氧化压力,表明污染环境中对水生生物的潜在风险.
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