相关实验视频
Updated: Sep 19, 2025

06:31
Force and Position Control in Humans - The Role of Augmented Feedback
Published on: June 19, 2016
8.0K
感官表现的模式和特定环境调制的胆反
Bin Yu1,2, Yuxuan Yue1, Chi Ren1
1Department of Neurobiology, Department of Neurosciences, Center for Neural Circuits and Behavior, Kavli Institute for Brain and Mind, and Halıcıoğlu Data Science Institute, University of California San Diego, La Jolla, CA, USA.
概括
大脑
科学领域:
- 神经科学
- 感官处理
- 胆固醇系统
背景情况:
- 优先考虑感官信息对于行为至关重要, 但机制尚不清楚.
- 基础前脑胆能神经元影响嗅觉球 (OB) 电路.
研究的目的:
- 在感官任务中研究胆能神经元如何调节OB电路.
- 确定OB胆能系统在嗅觉处理和行为中的作用.
主要方法:
- 在嗅觉任务和被动气味呈现过程中记录了OB胆能轴突的活性.
- 在嗅觉和听觉任务中检查了OB和背部皮质的胆能轴突反应.
- 不活化的OB-投射胆能神经元和对嗅觉任务的性能和OB神经活动的评估.
主要成果:
- 与口面运动相关的OB胆能轴突活动,而不是被动的气味.
- 在嗅觉任务中,OB胆能轴突转移到与气味相关的反应.
- 这种转移在背皮层投影或听觉任务中是不存在的.
- 胆固醇神经元不活化损害了嗅觉功能,并减少了OB颗粒细胞的嗅觉反应.
结论:
- 胆固醇系统可以动态调节感官处理.
- 这种调节是特定于模式和上下文的,对于适应性行为至关重要.
相关概念视频
Introduction to Special Senses
6.2K
Sensory receptors play an integral part in comprehending our external and internal environments. They receive diverse stimuli, converting them into the nervous system's electrochemical signals. This conversion occurs as the stimulus alters the sensory neuron's cell membrane potential, instigating the generation of an action potential. This action potential is subsequently transmitted to the central nervous system (CNS), which integrates with other sensory data or higher cognitive...
6.2K
Sensory Modalities
1.7K
Sensation typically is the process by which the sensory receptors and sense organs detect stimuli from the internal and external environment and transmit this information to the central nervous system for processing.
General senses refer to the broad category of sensory information detected by receptors in the body and can be further grouped into somatic and visceral senses. Somatic sensations include touch, pressure, temperature, and pain and are essential for navigating our environment and...
General senses refer to the broad category of sensory information detected by receptors in the body and can be further grouped into somatic and visceral senses. Somatic sensations include touch, pressure, temperature, and pain and are essential for navigating our environment and...
1.7K
Somatosensation
38.6K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
38.6K
Parasympathetic Signaling
2.2K
Parasympathetic signaling plays a crucial role in regulating various physiological processes. It involves the release of acetylcholine (ACh) by parasympathetic neurons, which can have localized and short-lived effects. The majority of ACh released is rapidly inactivated at the synapse by the enzyme acetylcholinesterase (AChE), which hydrolyzes Ach into choline and acetate. Additionally, the tissue cholinesterase deactivates any ACh diffusing into the surrounding tissues.
The effects of...
The effects of...
2.2K
Cholinergic Receptors: Muscarinic
3.3K
The pharmacological actions of acetylcholine are elicited via its binding to two families of cholinergic receptors or cholinoceptors, namely, muscarinic and nicotinic receptors. Muscarinic receptors are G protein-coupled receptors and have five subtypes, M1–M5. All mAChR subtypes are activated by acetylcholine and blocked by the antagonist, atropine.
The subtypes M1, M3, and M5 couple with the Gq subunit and activate the phospholipase C (PLC) activity, mobilizing intracellular Ca2+....
The subtypes M1, M3, and M5 couple with the Gq subunit and activate the phospholipase C (PLC) activity, mobilizing intracellular Ca2+....
3.3K
Sensory Perception: Organization of the Somatosensory System
7.0K
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
7.0K

