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在外周动脉疾病中混合重血管化程序的短期和长期结果:系统审查协议

Maram Darwish^1,2, Huw Owain Davies³, Emily Morgan^4,5

¹Vascular Surgery, Cardiff and Vale University Health Board, Cardiff, UK.

|June 19, 2025

概括

本系统性审查评估了对外围动脉疾病 (PAD) 混合重血管化的长期结果. 它旨在提供关于穿透性,肢体救援,生存和并发症的证据,以指导临床实践.

科学领域:

血管外科血管外科
干预心脏病学干预心脏病学
系统审查方法论系统审查方法论

背景情况:

周围动脉疾病 (PAD) 是一种普遍的疾病,与显著的发病率和死亡率有关.
混合重血管,结合开放的手术和内血管技术,越来越多地用于复杂的PAD.
对于混合重血管化手术,长期结果数据有限.

研究的目的:

系统地评估PAD患者混合重血管化的长期结果.
评估关键指标,包括穿透率,肢体救援,存活率,再干预率和并发症.
为临床实践和PAD管理的未来研究提供基于证据的见解.

主要方法:

遵守系统审查和元分析 (PRISMA) 准则的首选报告项目.
包括随机对照试验,队列研究,病例对照研究和至少1年后续的大型病例系列.
在主要数据库 (PubMed,Embase,Cochrane Library,CINAHL,ClinicalTrials.gov) 进行全面的文献搜索,独立提取数据和质量评估.

主要成果:

主要结局包括穿透率,肢体救援和生存.
二次结果包括并发症率,功能改善和生活质量.
将采用元分析和叙事综合,并通过子组分析探索影响因素.

结论:

该审查将综合有关PAD混合重血管化的有效性和安全性的现有证据.
结果将为临床决策提供信息,并确定进一步研究的领域.
这项研究旨在提高对这种复杂的PAD治疗方法的长期结果的理解.

关键词:

下肢的底部极端进行元分析分析.系统审查是系统的审查.血管医学血管医学血管外科血管外科

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