在急诊室使用推进剂量的上腺素 - - 一项多中心研究
Erin L Simon1, Matthew J Campbell2, Brianna Latta2
1Department of Emergency Medicine, Cleveland Clinic Akron General, Akron, Ohio; Northeast Ohio Medical University, Rootstown, Ohio.
The Journal of emergency medicine
|June 19, 2025
概括
推量上腺素 (PDE) 经常用于老年,重病急诊室患者的低血压. 大多数患者在接受PDE后需要额外的血管压缩剂输液.
科学领域:
- 紧急医疗 紧急医疗
- 关键的护理关键的护理
- 药理学 药理学是指药理学的学科.
背景情况:
- 推量上腺素 (PDE) 越来越多地在急诊室 (ED) 用于管理危急病患者的低血压.
- 关于PDE在ED环境中的安全性,剂量和疗效的现有数据是有限的,尽管它已在术后护理中得到证实.
研究的目的:
- 评估预填充上腺素注射器 (100微克/10毫升静脉注射) 的利用和剂量模式. 在EDs. bolus) 中使用.
- 为了确定在一个大型医疗保健系统内PDE管理后持续血管压缩剂输注的需要.
主要方法:
- 回顾性多站点队列研究分析了386名接受至少一剂PDE的患者.
- 数据包括人口统计,剂量,结果和随后的血管压缩剂使用.
- 描述性统计数据用于分析.
主要成果:
- 患者的中位数年龄为69岁;70.2%的患者在PDE后需要持续的血管压缩剂输液.
- 平均剂量为20μg的PDE,大多数患者接受一剂或两剂.
- PDE主要用于高急性病例 (ESI级别1和2); 81.9%的患者被送往重症监护室,15%的患者死亡.
结论:
- PDE通常用于老年患者,在ED中具有高急性疾病.
- 大多数患者在PDE后需要随后的血管压缩剂输液.
- 需要进一步的研究来评估预填注射器是否可以减少不良事件并改善ED患者的治疗结果.
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