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Updated: Sep 19, 2025

The CryoAPEX Method for Electron Microscopy Analysis of Membrane Protein Localization Within Ultrastructurally-Preserved Cells
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CryoEM提供了关于VPS15如何调节VPS34活动的详细见解

Robyn Duttenhefner1, Subeksha Subedi1, Sangita C Sinha1

  • 1Department of Chemistry and Biochemistry, North Dakota State University, Fargo, ND 58108-6050, USA.

Trends in biochemical sciences
|June 19, 2025
PubMed
概括

这种VPS15伪激酶结合了GTP和米里,稳定了不活跃的VPS34. 氨基酸释放激活了VPS34在膜上产生PI3P.

关键词:
结合GTP的伪基因酶在N-myristate的封存过程中.自自是自的过程.第三类的酸丁醇3-酶 (PI3KC3) 或真空蛋白排序蛋白34 (VPS34) 复合体.低温电子显微镜 (cryo-EM) 的使用真空蛋白质分类蛋白15 (VPS15) 是一种真空蛋白质分类蛋白15 (VPS15).

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