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Updated: Sep 18, 2025

Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues
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可塑性活性站点循环是高基质性质的关键吗? 混合,生物催化路径,以结构多样性高体侧链与显著的双立体控制

Gaurav P Kudalkar1, Florian Leidner2, Nivesh Kumar1

  • 1Department of Chemistry, University of Nebraska, Lincoln, NE, 68588-0304, USA.

Angewandte Chemie (International ed. in English)
|June 19, 2025
PubMed
概括

克洛斯特酸醇脱酶 (CaADH) 结构揭示了其基质乱交的洞察力. 这种酶使得用于癌症治疗的多种类型的体侧链的合成成为可能.

关键词:
克洛斯特里乙丁酒精脱酶 (CaADH) 的使用动态减小运动分辨率 (DYRKR)灵活的循环循环可以素结合是一种素结合.在Taxotere的侧链上.

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