跨关前列腺活检的回顾性,单一中心评估,省略了抗生素预防和省略了细菌性尿症的外干预查
Francois Leboutte1, Tim Schykowski2, Jeroen Van de Plas3
1Department of Urology, Krankenhaus der Barmherzigen Brüder Trier, Medical Campus Trier of the Johannes Gutenberg-University Mainz, Trier, Germany. f.leboutte@bbtgruppe.de.
World journal of urology
|June 19, 2025
概括
忽略跨关前列腺活检的抗生素预防是安全的,具有较低的传染性并发症率. 这支持了抗生素管理,并降低了成本和副作用.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 由于败血症风险较低,越来越多地建议进行跨关前列腺活检,而不是通过直肠活检.
- 跨膜活检的抗生素预防指南尚未标准化.
- 有关抗生素耐药性,副作用和与预防相关的成本存在担忧.
研究的目的:
- 评估跨腺前列腺活检中遗漏抗生素预防的安全性和有效性.
- 确定在没有抗生素预防的情况下接受跨关节前列腺活检的患者感染并发症的发生率.
主要方法:
- 对636名没有抗生素预防的经前列腺活检患者的回顾性分析 (2019年1月 - 2020年8月).
- 主要终点:干预后感染并发症的发生率.
- 二级终点:一般并发症和相关的危险因素.
主要成果:
- 整体并发症率为1.9%.
- 感染性并发症发生在1.1%的患者中 (前列腺炎,皮膜炎,住院治疗,尿液过敏).
- 传染性并发症和败血症的发生率低于抗生素预防的跨直肠活检报告的水平.
结论:
- 在跨关节前列腺活检中省略抗生素预防是相对安全的,感染并发症率较低.
- 研究结果支持合理的抗生素使用,有助于抗生素管理.
- 减少不必要的抗生素预防可以减轻耐药性,副作用和医疗费用.
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