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Updated: Sep 18, 2025

Direct Measurement of KDM1A Target Engagement Using Chemoprobe-based Immunoassays
11:17

Direct Measurement of KDM1A Target Engagement Using Chemoprobe-based Immunoassays

Published on: June 13, 2019

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表观遗传编辑和表观药物:一种组合策略,同时针对KDM4作为一种新型抗癌方法

Federica Sarno1,2, Jim J Jacob1, Roos E Eilers1

  • 1Epigenetic Editing Research Group, Department of Pathology and Medical Biology, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands.

Clinical epigenetics
|June 19, 2025
PubMed
概括

将表观遗传编辑与表观药物结合起来,可以提供一种协同作用的抗癌策略. 这种方法抑制KDM4基因表达和蛋白质活性,降低毒性并增强对各种癌症的治疗效果.

关键词:
在CRISPR/dCas9中使用.抗发炎药物 抗发炎药物表观遗传编辑 在表观遗传编辑.在JIB-04中,我们可以看到JIB-04.KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4 KDM4QC6352 是一个什么?

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