生涯暴露在农村-城市条件和晚年认知功能的寿命
Lingzhi Chu1,2, Yingyan Wu3, Heidi Karjalainen4
1Department of Environmental Health Sciences, Yale School of Public Health, New Haven, Connecticut, USA.
概括
童年生活在农村地区与较差的认知功能和晚年认知障碍风险增加有关. 这突显了认知健康结果的差异.
科学领域:
- 老年学是指老年学的学科.
- 公共卫生 公共卫生
- 认知神经科学 认知神经科学
背景情况:
- 有限的研究存在于终身农村城市居住对认知功能的影响.
- 了解这些关联对于解决健康差异至关重要.
研究的目的:
- 检查农村-城市居住模式与美国老年人的认知结果之间的关联.
- 调查童年,成年和住宅流动性对认知健康的具体影响.
主要方法:
- 分析了3073名65岁以上的美国成年人从健康和退休研究-协调认知评估协议中获得的数据.
- 利用线性和后勤回归来评估农村-城市居住和认知功能之间的关系,包括记忆,执行功能和语言流性.
- 根据住院病史,对轻度认知障碍 (MCI) 和痴呆症/MCI的风险进行了检查.
主要成果:
- 童年农村居住与较低的记忆力,执行功能和语言流性显著相关.
- 童年居住在农村的个人面临较高的轻度认知障碍 (MCI) 和痴呆/MCI风险.
- 与终身城市居民相比,那些在农村居住 (童年和/或成年) 的人表现出较差的认知功能和增加MCI风险.
结论:
- 农村居民一生,特别是在童年期间,与晚年认知功能下降有关.
- 研究结果强调需要有针对性的早期医疗干预措施,以减轻认知健康的农村和城市差异.
- 早期的生活环境对长期的认知健康起着至关重要的作用.
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