患者延迟和缺血性中风预后:系统性审查和元分析
Tong Zhang1, Jiangxia Qin2, Yanru Chen2
1Department of Emergency, Gansu Provincial Hospital, Lanzhou, China.
Clinical nursing research
|June 20, 2025
概括
患者延迟寻求治疗缺血性中风的预后明显恶化. 延迟访问增加了死亡,再入院,中风复发和不良结果的风险,突出了及时医疗护理的需要.
科学领域:
- 神经学 神经学
- 公共卫生 公共卫生
- 临床医学 临床医学
背景情况:
- 患者延迟寻求缺血性中风治疗是影响健康结果的关键因素.
- 延迟医疗照顾对缺血性中风患者预后的确切影响需要进一步阐明.
研究的目的:
- 进行系统性审查和元分析,以确定患者延迟和缺血性中风的预后结果之间的关联.
主要方法:
- 在多个数据库 (PubMed,科学网,Embase等) 中进行全面的搜索. 在2022年7月24日之前进行.
- 包括的研究包括病例控制,队列和随机对照试验,其中数据被提取并由两个独立审查员评估偏差风险.
- 用Revman 5.3.5软件对14项涉及25337名患者的研究数据进行了元分析.
主要成果:
- 延迟访问的患者死亡率 (OR=2.03),再入院率 (OR=8.17),中风复发率 (OR=2.66) 和不良结果 (OR=2.07) 显著增加.
- 在国家卫生研究院中风评分表中,在延迟和及时访问组 (MD=1.12) 之间没有观察到统计学上显著的差异.
结论:
- 患者延迟是缺血性中风预后不佳的重要决定因素,增加了死亡率,再入院,复发和不良事件的可能性.
- 需要进一步的研究来验证和扩展这些发现,以了解延迟护理对缺血性中风结果的影响.
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