唾液腺质症的进化形状模型
Álvaro Sánchez Barrueco1,2,3, María Victoria López-Acevedo Cornejo4, William Aragonés Sanzen-Baker1,2,3
1Medicine Faculty, Alfonso X el Sabio University, Madrid, Spain.
唾液结石 (sialoliths) 是通过在有机核心周围的分层过程形成的,受到细菌的影响. 这项研究揭示了sialolith形成的通用模型,有助于理解和潜在的治疗策略.
科学领域:
- 矿物学是什么?矿物学是什么?
- 生物矿物化 生物矿物化
- 病理学 病理学 病理学
背景情况:
- 唾液结石 (sialoliths) 是唾液腺中的化沉积物,影响腺功能.
- 它们的形成涉及有机和无机沉,但详细的结构模型正在演变.
- 了解sialolith结构是制定有针对性的预防和治疗干预措施的关键.
研究的目的:
- 阐明人体体内石灰岩的详细结构和组成.
- 为了调查sialolith形态,矿物成分和解剖位置之间的关系.
- 提出一个统一的形状模型,用于sialolith形成.
主要方法:
- 使用扫描电子显微镜与能量分散式X射线光谱学 (SEM-EDX) 和X射线衍射 (XRD) 分析了来自102名患者的137个sialoliths.
- 从大学医院的病人身上通过sialendoscopy,直接提取或自发挤出获得Sialoliths.
- 进行了结构和矿物学表征,以确定组件和形成模式.
主要成果:
- 下腺体占西奥利的82%,口腔腺体占18%.
- 石灰岩石表现出一个有中央核心和同心层的石结构,经常与细菌相关.
- 主要的矿物成分包括八酸 (OCP),酸和whitlockite,较大的石头显示了酸结晶度的增加.
结论:
- 石灰岩有着共同的石结构和矿物成分,无论其来源如何.
- 形成涉及有机球体周围的异质核,细菌的影响,以及渐进的分层和结晶.
- 一个整合有机,无机和细菌因素的通用构造模型解释了sialolith的发展.
更多相关视频
08:03Isolation of Salivary Epithelial Cells from Human Salivary Glands for In Vitro Growth as Salispheres or Monolayers
Published on: July 15, 2019
07:38Radiation Treatment of Organotypic Cultures from Submandibular and Parotid Salivary Glands Models Key In Vivo Characteristics
Published on: May 17, 2019
相关概念视频
Salivary Glands and Saliva
Renal Tubule and Collecting Duct
Proximal Convoluted Tubule (PCT):
The PCT is the initial segment of the renal tubule, extending from the Bowman's capsule that encloses the glomerulus. Its convoluted structure and microvilli-lined cells increase the surface area for reabsorption. The PCT reabsorbs glucose, amino acids, sodium, and water from the filtrate, ensuring essential...
Urinary Tract Calculi I: Introduction
Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
Physiology of the Genitourinary System II: Tubular Reabsorption and Secretion
Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations
