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急性胰腺炎住院结果的性别相关差异:回顾性分析
Ahmed Ali Aziz1, Muhammad Ali Aziz2, Nosheen Omar3
1Internal Medicine, Integris Baptist Medical Center, Oklahoma City, USA.
Cureus
|June 20, 2025
概括
与男性相比,急性胰腺炎 (AP) 住院的女性患者经历了更好的结果,包括较低的死亡率,急性功能衰竭,败血症和休克. 住宿时间和费用在两性之间是相似的.
科学领域:
- 胃肠病学 胃肠病学
- 临床结果研究研究
- 健康差异 在健康上的差异
背景情况:
- 急性胰腺炎 (AP) 是一种普遍的胃肠道疾病,需要住院治疗.
- 了解影响AP患者结果的因素对于有效的临床管理至关重要.
- 在AP结果中基于性别的差异仍然是需要调查的领域.
研究的目的:
- 调查性别对急性胰腺炎住院成人患者住院治疗结果的影响.
- 为了比较男性和女性AP患者之间的死亡率,停留时间,医疗费用和并发症率.
主要方法:
- 2020年全国住院患者样本 (NIS) 数据库的回顾性分析.
- 包括使用ICD-10-CM代码诊断出急性胰腺炎的成年患者.
- 住院结局的比较,包括死亡率,住院时间,医疗费用,急性功能衰竭,败血症,休克和ICU入院.
- 多变量逻辑回归分析,以确定结果的独立预测因素,并调整混因素.
主要成果:
- 总共分析了252595名患有AP的成年患者.
- 与男性相比,女性患者在住院死亡率 (aOR:0.64),急性功能衰竭 (aOR:0.72),败血症 (aOR:0.68) 和休克 (aOR:0.74) 的几率明显较低.
- 没有观察到性别之间的住院时间,住院总费用或ICU入院率的统计学上显著差异.
结论:
- 与男性患者相比,急性胰腺炎的女性患者表现出明显改善的临床结果.
- 性别似乎没有影响停留时间,住院费用或AP的ICU入院.
- 需要进一步的研究来阐明这些观察到的基于性别的结果差异背后的机制,以告知临床实践.
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