通过代谢编程,LKB1调节ILC3的产后发育和效应器功能

Huasheng Zhang1,2,3, Linfeng Zhao1,2,3, Qingbing Zhang1,2,3

  • 1Center for Immune-Related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

PubMed
概括

肝激酶B1 (LKB1) 对第3组先天性淋巴细胞 (ILC3) 的发展和功能至关重要,这些细胞对肠道免疫至关重要. 缺乏LKB1会损害ILC3s,影响肠道平衡和宿主防御.

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