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儿童百日咳的临床特征和危险因素
1Department of Community Health Nursing, Alddrab University College, Jazan University, Jazan, SAU.
迟延或不接种白喉,结节和百日咳 (DTP) 疫苗会增加儿童的百日咳风险. 及时的DTP免疫和隔离是预防百日咳感染的关键.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- 百日咳,也称为百日咳,仍然是一个重要的公共卫生问题,特别是在婴儿和幼儿中.
- 了解临床特征和风险因素对于有效的预防和管理至关重要.
研究的目的:
- 调查临床特征并确定儿科患者咳的危险因素.
- 为了比较患有 pertussis 的儿童和患有咳的对照组之间的临床和实验室发现.
主要方法:
- 对100名被诊断患有 pertussis 的儿童和100名咳的儿童 (对照组) 的回顾性分析.
- 收集的数据包括临床特征,危险因素和实验室指数 (血清环球蛋白,IgM,CRP,WBC).
- 评估了疫苗接种状况,特别是喉,结和百日咳 (DTP) 疫苗的接种情况.
主要成果:
- 与对照组相比,患有 pertussis 的儿童表现出较低的血清球蛋白和免疫球蛋白 M (IgM) 水平.
- 较高的C-反应蛋白 (CRP),白细胞 (WBC) 计数和更长的住院时间在百日咳组中被观察到.
- 在患有 pertussis 的儿童中,发现明显更高的延迟或非免疫接种 diphtheria,tetanus和 pertussis (DTP) 疫苗的比率.
结论:
- 延迟或缺少DTP疫苗接种是儿童咳感染的重要危险因素.
- 强调及时接种 pertussis 疫苗和隔离措施在减少疾病发病率方面的关键作用.
- 强调需要强有力的免疫计划来保护脆弱的儿科人口.
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