功能性排泄障碍中的alexithymia:发生率和对治疗的影响
Sai Nan Shi1,2, Bin Bin Zhu1, Mei Feng Wang1
1Department of Gastroenterology, The First Affiliated Hospital with Nanjing Medical University, Nanjing, Jiangsu Province, China.
Journal of digestive diseases
|June 20, 2025
概括
亚历克西西米亚影响近30%的功能性排便障碍患者,恶化症状并降低治疗成功率. 早期识别是FDD管理更好的结果的关键.
科学领域:
- 胃肠病学 胃肠病学
- 精神病学是一个精神病学.
- 临床医学 临床医学
背景情况:
- 功能性排便障碍 (FDD) 在诊断和治疗方面存在重大挑战.
- 亚历克西西米亚的特点是难以识别和描述情绪,在FDD群体中尚未得到广泛研究.
研究的目的:
- 确定诊断为功能性排泄障碍 (FDD) 的患者中alexithymia的患病率.
- 评估alexithymia对FDD症状的严重性,生活质量和治疗结果的影响.
主要方法:
- 129名患有FDD的患者接受了高分辨率的直肠测量和气球驱逐测试.
- 症状严重程度 (PAC-SYM),生活质量 (PAC-QOL),焦虑 (SAS) 和抑郁 (SDS) 在基线和药物治疗4周后进行评估.
- 多伦多的alexithymia Scale-20被用来确定alexithymia.
主要成果:
- 在29.5%的FDD患者中发现了alexithymia.
- 与没有alexithymia的患者相比,患有alexithymia的患者在便秘症状,生活质量受损,焦虑和抑郁方面表现出更高的基线得分.
- 治疗后,alexithymia组的肠道排便频率,症状得分,生活质量,焦虑和抑郁症的改善明显较小.
- 多伦多亚历克西西米亚20级得分高是FDD药物治疗失败的独立预测指标.
结论:
- 亚历克西西米亚是功能性排便障碍患者常见的并发症.
- 亚历克西西米亚的存在与更严重的症状,更差的生活质量和减少FDD治疗疗效有关.
- 查alexithymia可能有利于优化治疗策略和改善FDD患者的结果.
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