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Updated: Sep 18, 2025

Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations
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Heuristic Mining of Hierarchical Genotypes and Accessory Genome Loci in Bacterial Populations

Published on: December 7, 2021

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在细菌泛基体中以链接为基础的ortolog精细化,使用CLARC

Indra González Ojeda1,2, Samantha G Palace1,3, Pamela P Martinez4

  • 1Center for Communicable Disease Dynamics, Department of Epidemiology, T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, United States.

Nucleic acids research
|June 20, 2025
PubMed
概括

通过改进对正统组 (COG) 集群的定义,CLARC通过改进细菌泛基因组分析. 这种方法精确地减少了辅助基因估计,增强了比较基因组学中的进化预测.

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An Integrated Approach for Microprotein Identification and Sequence Analysis

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CAPRRESI: Chimera Assembly by Plasmid Recovery and Restriction Enzyme Site Insertion

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Genome comparison is one of the excellent ways to interpret the evolutionary relationships between organisms. The basic principle of genome comparison is that if two species share a common feature, it is likely encoded by the DNA sequence conserved between both species. The advent of genome sequencing technologies in the late 20th century enabled scientists to understand the concept of conservation of domains between species and helped them to deduce evolutionary relationships across diverse...
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The DNA replication, transcription, and translation processes are intricately coupled in bacteria, allowing efficient gene expression and rapid protein synthesis. While this physical and functional coordination is advantageous, it introduces challenges that bacteria overcome through specific regulatory mechanisms.Coupling of Replication, Transcription, and TranslationThe coupling of replication, transcription, and translation is a hallmark of bacterial gene expression. As the replisome unwinds...
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