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Updated: Sep 18, 2025

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一个氧基化烯酸胺的药理学支架,用于SelU抑制

Stephen J Dansereau1,2, Alexander Shekhtman1,2, Salvatore Genovese3

  • 1Department of Chemistry and University at Albany, State University of New York, 1400 Washington Ave., Albany, NY, 12222, USA.

Chembiochem : a European journal of chemical biology
|June 20, 2025
PubMed
概括

研究人员选氧化烯酸作为潜在的药物候选者,向tRNA2-氨酸氨基合成酶 (SelU),这是一个对细菌基对忠诚度至关重要的酶. 这项研究确定了一个有前途的药理学支架,用于开发新型抗生素.

关键词:
2 - - 氨酸合成酶的作用.经过一段时间的经验,Geranylation.氧乙烯化烯化.化是一种化.

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