皮肤上的SARS-CoV-2生存率及其从受污染的表面转移
Ana K Pitol1, Samiksha Venkatesan1, Siobhan Richards1
1Liverpool School of Tropical Medicine, Departments of Vector Biology and Tropical Disease Biology, Centre for Neglected Tropical Diseases, Liverpool, United Kingdom.
PloS one
|June 20, 2025
概括
这项研究表明,SARS-CoV-2有效地从塑料和金属表面转移到皮肤模型,但不是干纸板. 皮肤上的病毒存活率随着温度的提高而显著下降.
科学领域:
- 病毒学 病毒学
- 流行病学 流行病学
- 公共卫生 公共卫生
背景情况:
- 了解通过虫传播的SARS-CoV-2传播对于控制COVID-19至关重要.
- 关于SARS-CoV-2在皮肤上的传输效率及其存活时间的数据有限.
研究的目的:
- 量化SARS-CoV-2从各种表面转移到3D皮肤模型.
- 为了确定不同温度下皮肤上的SARS-CoV-2生存率.
主要方法:
- 使用菌 Phi 6 验证了一个 3D 皮肤模型 (LabSkin).
- 评估了SARS-CoV-2从塑料,金属和纸板转移到LabSkin.
- 在受控温度下测量SARS-CoV-2在皮肤上的生存时间.
主要成果:
- 实验室皮肤准确地模仿了人类皮肤进行病毒传输.
- 从塑料和金属中,SARS-CoV-2的传输效率为~13%;从干纸板中没有.
- 病毒在皮肤上的半衰期从2.8小时到17.8小时不等,随着温度的升高而下降.
结论:
- 非多孔的表面对SARS-CoV-2通过fomites传播的风险更高.
- 温度显著影响SARS-CoV-2在皮肤上的生存,影响传播动态.
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