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在重症监护病房的败血症患者中90天死亡率的风险因素分析
Yuntian Xu1, He Zhang2, Jiezhi Li3
1Department of Critical Care Medicine, The Third Affiliated Hospital of Anhui Medical University, Hefei First People's Hospital, Hefei, China.
在ICU中的败血症患者的死亡率很高. 这项研究发现,身体组成,特别是骨肌肉密度,面积和指数,是预测败血症患者90天生存时间的关键指标.
科学领域:
- 关键护理医学 关键护理医学
- 放射学 放射学是一门学科.
- 医疗成像医学成像
背景情况:
- 败血症仍然是重症监护室 (ICU) 死亡的主要原因.
- 鉴定败血症患者可靠的预后因素对于改善结果至关重要.
- 之前的研究还没有充分探讨身体成分在败血症死亡率中的作用.
研究的目的:
- 调查体质成分参数与败血症患者90天死亡率之间的关联.
- 为了确定特定的腹部CT-评估的身体组成指标作为毒症的潜在预后因素.
主要方法:
- 对123名进入中国医院的败血症患者的回顾性研究 (2015年1月 - 2018年12月).
- 在幸存者和非幸存者之间比较临床和腹部CT数据.
- 逻辑回归,Cox回归和Kaplan-Meier生存分析是在CT衍生体质成分指数上进行的.
主要成果:
- 在幸存者和非幸存者之间观察到骨肌密度 (SMD),骨肌面积 (SMA),骨肌指数 (SMI) 和皮下脂肪组织面积 (SAT) 的显著差异.
- 较高的SMD,SMA和SMI显著与较低的90天死亡率相关 (Cox回归分析).
- 卡普兰-梅尔曲线显示出基于中位数SMI的明显生存差异.
结论:
- 腹部CT评估的身体组成参数与ICU败血症患者的90天死亡率密切相关.
- 骨肌密度 (SMD),骨肌面积 (SMA) 和骨肌指数 (SMI) 被确定为有价值的预后指标.
- 这些来自成像的指标可以帮助分层风险和治疗败血症.
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