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Updated: Sep 18, 2025

Analysis of LINE-1 Retrotransposition at the Single Nucleus Level
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Analysis of LINE-1 Retrotransposition at the Single Nucleus Level

Published on: April 23, 2016

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脊椎动物R2逆转移素复合物的结构在目标原始反转录过程中和第二链切割后

Akanksha Thawani1,2, Anthony Rodríguez-Vargas2, Briana Van Treeck2

  • 1California Institute for Quantitative Biosciences (QB3), Berkeley, CA, USA.

Science advances
|June 20, 2025
PubMed
概括

脊椎动物R2蛋白精确地将基因插入到核糖体RNA位点. 高分辨率结构揭示了这些逆转移子如何识别DNA并促进基因插入,从而使未来的基因工程应用成为可能.

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