自主神经系统功能与内淋巴体空间比率在Ménière病中的关系
Keita Ueda1, Tomoyuki Shiozaki1, Hiroshi Inui2
1Department of Otorhinolaryngology-Head and Neck Surgery, Nara Medical University, 840 Shijo, Kashihara City, Nara 6348522, Japan.
Auris, nasus, larynx
|June 20, 2025
概括
自主功能障碍可能在Ménière病 (MD) 中起到更大的作用,而不是良性发性定位 (BPPV). 在MD患者中,Schellong测试呈阳性,尾内淋巴体空间比率增加与缩血压降低相关.
科学领域:
- 神经学 神经学
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 心脏病学 心脏病学
背景情况:
- 自主功能障碍与梅尼耶氏病 (MD) 和良性性定位 (BPPV) 有关.
- 定位血压 (BP) 和心率 (HR) 的变化可以评估自主神经系统 (ANS) 功能.
- 内耳结构,特别是内淋巴空间 (ELS),可能会受到ANS功能的影响.
研究的目的:
- 为了研究MD/BPPV和ANS功能之间的关系.
- 在MD和BPPV患者中分析BP,HR和ELS比率.
- 为了确定MD和BPPV之间的ANS功能和内耳结构的差异.
主要方法:
- 对168名被诊断患有MD (n=103) 或BPPV (n=65) 的患者进行了回顾性分析.
- 内耳MRI用于ELS比率计算 (整体,耳,前庭,半圆通道).
- 施勒龙测试 (S-测试) 和HR测量,以评估在位置变化期间的自主功能.
主要成果:
- 与BPPV患者 (23.1%) (P=0.0427) 相比,MD患者 (38.8%) 的比例显著更高,S测试呈阳性.
- 在MD患者中,S测试呈阳性,趋势显示耳ELS比率增加与缩血压降低相关 (r=-0.346,P=0.0287).
- 在其他组合组中没有发现显著差异.
结论:
- 美国神经系统功能似乎比BPPV更能影响MD的发病.
- 在MD患者中,耳ELS比率增加和静脉血压降低之间存在微弱的相关性,患者的S-测试呈阳性.
- 这些发现表明,自主调节与MD的内耳变化之间存在潜在的联系.
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