有或没有力量训练的高蛋白饮食对老年人氧化应激标志物没有负面影响
Laura Bragagna1, Lina Maqboul2, Ricarda Baron2
1Department of Nutritional Sciences, University of Vienna, Austria; Research Platform Active Aging, University of Vienna, Austria; Vienna Doctoral School for Pharmaceutical, Nutritional and Sport Sciences (PhaNuSpo), Vienna, Austria.
Redox biology
|June 20, 2025
概括
高蛋白饮食与力量训练相结合并没有显著改变老年人的氧化应激标志物. 虽然一些血液标记物发生了变化,但这些影响是轻微的,并没有表明对健康有重大影响.
科学领域:
- 老年学是一门学科.
- 营养科学 营养科学
- 运动生理学 运动生理学
背景情况:
- 老龄化社会的目标是长寿,健康的生活,但减少体力活动会导致肉症.
- 力量训练和足够的蛋白质摄入量对于抵消与年龄相关的肌肉损失和不活动至关重要.
- 氧化应激标记是细胞健康和衰老过程的重要指标.
研究的目的:
- 研究高蛋白饮食与力量训练对老年人氧化应激标志物的影响.
- 在17周的干预期内分析血液参数和特定氧化应激指标的变化.
主要方法:
- 一项为期17周的单盲随机对照试验,涉及116名老年人 (对照组,建议蛋白质组,高蛋白质组).
- 最初6周的饮食干预,然后对蛋白质组进行力量训练.
- 在基线,第8周和研究完成时分析的血液样本,用于各种生化和氧化应激标志物.
主要成果:
- 在血液参数和氧化应激标志物中观察到显著的时间效应,可能是由于季节性变化.
- 高蛋白摄入导致尿素和血液尿素 (BUN) 的增加,但在正常范围内.
- 在高蛋白组中,非结合性胆红素 (UCB) 和铁降解能力潜力 (FRAP) 较低.
- 高蛋白质组的女性显示氧化应激标志物发生变化和尿酸 (UA) 减少,可能与雌激素分泌和抗氧化剂防御通路有关.
结论:
- 高蛋白饮食与力量训练相结合并没有显著影响老年人的整体氧化应激.
- 观察到的特定标记物 (尿素,BUN,UCB,FRAP,UA) 的变化表明,对高蛋白摄入量的代谢适应.
- 仅仅是力量训练并没有对测量血液或氧化应激参数产生负面影响.
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