富含黄胺的饮食与慢性病风险降低有关:一项前性队列研究
William Bell1, Alysha S Thompson1, Nicola P Bondonno2
1Co-Centre for Sustainable Food Systems and Institute for Global Food Security, Queen's University Belfast, Northern Ireland, UK.
Clinical nutrition (Edinburgh, Scotland)
|June 20, 2025
概括
在果和果等食物中发现的富含黄胺的饮食与慢性病 (CKD) 的风险降低以及CKD患者的死亡率降低有关. 增加这些富含黄类食物的摄入量可能会改善脏健康.
科学领域:
- 营养流行病学 营养流行病学
- 心血管健康 心血管健康
- 腎臟病學 (nephrology) 是一種醫學.
背景情况:
- 机理学研究表明,黄类药物有益于功能.
- 没有大规模的前性队列研究研究了黄类药物摄入量和病.
- 这项研究通过检查与慢性病 (CKD) 风险和死亡率相关的黄类摄入量来弥补这一差距.
研究的目的:
- 调查黄类药物摄入量与患CKD的风险之间的关联.
- 检查已经被诊断患有CKD的个体中黄类摄入量和全因死亡率之间的关系.
- 探索这些协会的潜在调解机制.
主要方法:
- 一项基于人口的前性研究,涉及109,711名年龄在40-69岁之间的成年人.
- 评估的饮食摄入量使用≥2个24小时的回忆来计算黄素饮食评分 (FDS).
- 用于评估CKD风险和全因死亡率的多变量考克斯回归分析;调解分析探索了机制.
主要成果:
- 较高的FDS (中位数为6份/天) 与发生性CKD风险降低16%有关 (P<0.001).
- 关联的部分介导是甘油三,HDL,HbA1c,cystatin-C和CRP的改善.
- 在CKD患者中,更高的FDS与全因死亡率降低27%的风险有关 (P=0.10).
结论:
- 富含黄胺的饮食,平均每天6份,与中年成人中低的CKD风险有关.
- 增加摄入富含黄类食物,如果和果,可能会降低CKD风险,并改善CKD患者的预后.
- 简单的饮食修改,专注于黄类摄入量,对脏健康管理有很大的前景.
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