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Updated: Sep 18, 2025

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出版偏差对支持使用近视控制干预措施的证据的影响
Giulia Carlotta Rizzo1, Lorenza Scotti2, Alberto Recchioni3
1Department of Materials Sciences, University of Milano-Bicocca, Milan, Italy; Research Centre in Optics and Optometry (COMiB), University of Milano-Bicocca, Milan, Italy.
概括
出版偏见似乎不会影响近视控制研究. 对现有研究的分析表明,对近视控制干预措施的有效性不太可能被高估.
科学领域:
- 眼科医生 眼科 眼科
- 临床研究 临床研究
- 生物统计学 生物统计学
背景情况:
- 发表偏见,即负面结果的研究不太可能发表,可能会扭曲治疗的感知有效性.
- 评估出版偏见对于准确解释近视控制干预措施的证据至关重要.
研究的目的:
- 评估出版偏见对近视控制干预现有证据的影响.
- 为了确定当前近视控制治疗的疗效是否因出版偏差而被高估.
主要方法:
- 对近视控制干预措施的系统审查和元分析进行系统的文献搜索.
- 包括随机对照试验 (RCT) 评估基于眼镜,隐形眼镜 (CL) 和药物治疗.
- 使用漏斗图和埃格尔对轴长度和折射误差结果的测试来评估出版偏差.
主要成果:
- 分析包括27个系统审查/元分析和49个RCT.
- 埃格尔的测试表明了药理治疗 (轴长) 和CL (折射误差) 的潜在偏差,但修剪和填充分析没有证实过高估计的疗效.
- 像阿特罗宾和多焦点CL这样的特定治疗方法在埃格尔测试结果中没有显著的结果.
结论:
- 没有发现出版偏差的显著证据,以影响当前关于近视控制治疗的文献.
- 控制近视的干预措施,包括眼镜,隐形眼镜和药物剂的有效性不太可能被高估.
- 这表明当前近视控制策略的可靠证据基础.
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